Acantholysis and dyskeratosis are the typical histological findings. 棘层松解和角化不良是典型的病理改变。
Unchecked telomere loss by HSC, meanwhile, would appear to play a significant role in the pathogenesis of bone marrow failure, as observed in the condition dyskeratosis congenita. 当观察到角化不良的现象时，端粒缺失可能在骨髓衰竭的发病中起关键作用。
Acantholysis and dyskeratosis are the typical histological findings. 棘层松解和角化不良是典型的病理改变。
Unchecked telomere loss by HSC, meanwhile, would appear to play a significant role in the pathogenesis of bone marrow failure, as observed in the condition dyskeratosis congenita. 当观察到角化不良的现象时，端粒缺失可能在骨髓衰竭的发病中起关键作用。
