Mismatch repair gene defects are recently identified in hematopoietic malignancies, leukemia and lymphoma cell lines. 错配修复基因缺陷是最近在造血系统恶性肿瘤，白血病和淋巴瘤细胞株中被发现的。
They found that knocking out the gene in fetal mice whose hematopoietic systems had already formed caused hematopoietic stem cells to disappear. 他们发现击昏已经形成造血系统的胚胎小鼠的基因会引起造血干细胞的消失。
