intragenic

英[ɪntrə'dʒenɪk] 美[ɪntrə'dʒenɪk]
  • adj. [生]基因内的
1. Both frameshift and missense mutations can be suppressed by intragenic suppressors.
移码突变和异义突变都能被基因内抑制基因所抑制。

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2. Both frameshift and missense mutations can be suppressed by intragenic suppressors.
两个突变发生在同一基因内的抑制,叫基因内抑制。

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3. It is necessary to detect the large intragenic MMR genes deletions in the molecular detection of HNPCC.
在分子遗传学检测中有必要开展MMR基因大片段缺失的检测。

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4. The intragenic and extragenic recombination results in variation. Recombination also is involved in generation novel resistance specificities.
基因间和基因内重组导致了变异,也导致了新特异性抗病基因的产生。

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5. Methods: Using the polymerase chain reaction technique (PCRT), LOHs in 10 samples of hereditary ovarian cancer at intragenic loci were detected.
方法:应用多聚合酶链反应技术(PCRT),对10份遗传性卵巢癌组织中BRCA1基因内部的D17S855微卫星位点进行LOH检测。

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6. Conclusions No functional FANCA protein was found in these 3 cases of FA-A, and intragenic deletion, frame shift and splice site mutation were the major pathogenic mutations found in FANCA gene.
结论3例FA-A型患者均无功能性FANCA蛋白表达;基因缺失、移码突变和剪切位点突变是FANCA基因的主要失活方式。

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7. Conclusions No functional FANCA protein was found in these 3 cases of FA-A, and intragenic deletion, frame shift and splice site mutation were the major pathogenic mutations found in FANCA gene.
结论3例FA-A型患者均无功能性FANCA蛋白表达;基因缺失、移码突变和剪切位点突变是FANCA基因的主要失活方式。

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    用作形容词 (adj.)
    1. Suppression is called intragenic when both mutations are within the same gene.
      两个突变发生在同一基因内的抑制,叫基因内抑制。