Paracetamol taken in high doses may effect the use of metoclopramide, domperidone and anticoagulants including warfarin. 大量服用扑热息痛可能会使胃复安，多潘立胴，抗凝血剂失去效用。
Metoclopramide increases the tone of the lower esophageal sphincter as well as facilitating gastric emptying. 胃复安促进胃排空的同时可以增加食道下端括约肌张力。
