However, the cellular and molecular basis of asymmetric morpho-genesis remains largely unknown. 然而，不对称形态发生的细胞和分子基础基本上仍然是不清楚的。
The molecular basis of chemoresistance is poorly understood, precluding advances in glioma treatment and leaving gliomas among the most lethal tumors. 药物抵抗的分子基础尚未被很好的阐明，排除了对治疗敏感的胶质瘤，而留下的胶质瘤便是最为致命性的。
