Trichloroacetic acid is the most sensitive and specific in these acid and is used widely. 溶液中的蛋白亦能被有机酸沉淀，其中以三氯醋酸的作用最为灵敏而且特异，因此广泛的被用于沉淀蛋白质。
Because it is a corrosive acid, it must be "buffered" to damp down the acidity, and it is usually administered as sodium dichloroacetate. 由于它是一种有腐蚀性的酸类物质，需要用中和的办法以减弱其酸性，因此用于服用者多是二氯醋酸钠。
