In advanced breeding programs, parental differences and variability in hybrid progeny may largely reside in multiple gene systems. 在当代的育种计划里，亲本的差异和杂种后代的变异，可能绝大部分都属于多基因系统。
Gene Mapping of human diseases, especially the complex genetic diseases, has been the difiiculty and hotspot in medical genetics and gene study. 人类疾病，特别是多基因遗传病相关基因的定位，是目前医学遗传学和基因研究中的难点和热点。
