Directed evolution has been proven to be an effective method for proteins engineering. 体外定向进化是蛋白质工程中一个非常有效的设计策略。
Protein engineering and site directed mutagenesis have been used to change the active site and alter the substrate specificity of various hydroxynitrile lyases. 研究人员已经利用蛋白质工程和定点突变技术来改变各种醇腈酶的活性位点和底物特异性等。
